markdown-mermaid-writing skill (K-Dense scientific-agent-skills)
- Install
- SKILL.md (verbatim)
- Overview
- When to Use This Skill
- π¨ The Source Format Philosophy
- Why text-based diagrams win
- The three-phase workflow
- What Mermaid can express
- π§ Core workflow
- Step 1: Identify the document type
- Step 2: Read the style guide
- Step 3: Pick the diagram type and read its guide
- Step 4: Write the document
- Step 5: Commit as text
- β οΈ Common pitfalls
- Radar chart syntax (radar-beta)
- XY Chart vs Radar confusion
- Forgetting accTitle/accDescr on supported types
- π Integration with other skills
- With scientific-schematics
- With scientific-writing
- With literature-review
- With any skill that produces output documents
- π Reference index
- Style guides
- Diagram type guides (24 types)
- Document templates (9 types)
- Examples
- π Attribution
- Other files in this skill
- assets/examples/example-research-report.md (verbatim)
- π Overview
- π Experimental workflow
- π¬ Methods
- Cell lines and culture
- gRNA design and efficiency prediction
- Transfection protocol
- Analysis pipeline
- π Results
- Editing efficiency by cell line
- Effect of GC content on efficiency
- Timeline of key experimental milestones
- π Discussion
- Why HEK293T outperforms suspension lines
- Comparison with published benchmarks
- π― Conclusions
- π References
- references/diagrams/architecture.md (verbatim)
- Exemplar Diagram
- Tips
- Template
- Complex Example
- Why this works
- references/diagrams/block.md (verbatim)
- Exemplar Diagram
- Tips
- Template
- Complex Example
- Why this works
- references/diagrams/c4.md (verbatim)
- Exemplar Diagram β System Context
- C4 Zoom Levels
- Tips
- Template
- Complex Example
- Why this works
- references/diagrams/class.md (verbatim)
- Exemplar Diagram
- Tips
- Template
- Complex Example
- Why this works
- references/diagrams/gitgraph.md (verbatim)
- Exemplar Diagram
- Tips
- Template
- references/diagrams/mindmap.md (verbatim)
- Exemplar Diagram
- Tips
- Template
What it does. Comprehensive markdown and Mermaid diagram writing skill. Use when creating any scientific document, report, analysis, or visualization. Establishes text-based diagrams as the default documentation standard with full style guides (markdown + mermaid), 24 diagram type references, and 9 document templates. Part of K-Dense-AI/scientific-agent-skills (AI Scientist skills) (K-Dense-AI/scientific-agent-skills).
| Upstream | K-Dense-AI/scientific-agent-skills |
| Skill file | skills/markdown-mermaid-writing/SKILL.md |
| License | MIT |
| Author | K-Dense Inc. |
| Fetched | 2026-09-10 |
Install
npx skills add K-Dense-AI/scientific-agent-skills --skill markdown-mermaid-writing, or copy the skill folder into~/.claude/skills/markdown-mermaid-writing/.- Raw file:
curl -sL https://raw.githubusercontent.com/K-Dense-AI/scientific-agent-skills/HEAD/skills/markdown-mermaid-writing/SKILL.md
SKILL.md (verbatim)
name: markdown-mermaid-writing
description: Comprehensive markdown and Mermaid diagram writing skill. Use when creating any scientific document, report, analysis, or visualization. Establishes text-based diagrams as the default documentation standard with full style guides (markdown + mermaid), 24 diagram type references, and 9 document templates.
allowed-tools: Read Write Edit Bash
license: Apache-2.0
metadata:
version: "1.1"
skill-author: Clayton Young / Superior Byte Works, LLC (@borealBytes)
skill-source: https://github.com/SuperiorByteWorks-LLC/agent-project
skill-version: 1.0.0
skill-contributors: Clayton Young (Superior Byte Works, LLC / @borealBytes; Author and originator); K-Dense Team (K-Dense Inc.; Integration target and community feedback)
Markdown and Mermaid Writing
Overview
This skill teaches you β and enforces a standard for β creating scientific documentation using markdown with embedded Mermaid diagrams as the default and canonical format.
The core bet: a relationship expressed as a Mermaid diagram inside a .md file is more
valuable than any image. It is text, so it diffs cleanly in git. It requires no build step.
It renders natively on GitHub, GitLab, Notion, VS Code, and any markdown viewer. It uses
fewer tokens than a prose description of the same relationship. And it can always be
converted to a polished image later β but the text version remains the source of truth.
"The more you get your reports and files in .md in just regular text, which mermaid is as well as being a simple 'script language'. This just helps with any downstream rendering and especially AI generated images (using mermaid instead of just long form text to describe relationships < tokens). Additionally mermaid can render along with markdown for easy use almost anywhere by humans or AI."
β Clayton Young (@borealBytes), K-Dense Discord, 2026-02-19
When to Use This Skill
Use this skill when:
- Creating any scientific document β reports, analyses, manuscripts, methods sections
- Writing any documentation β READMEs, how-tos, decision records, project docs
- Producing any diagram β workflows, data pipelines, architectures, timelines, relationships
- Generating any output that will be version-controlled β if it's going into git, it should be markdown
- Working with any other skill β this skill defines the documentation layer that wraps every other output
- Someone asks you to "add a diagram" or "visualize the relationship" β Mermaid first, always
Do NOT start with Python matplotlib, seaborn, or AI image generation for structural or relational diagrams. Those are Phase 2 and Phase 3 β only used when Mermaid cannot express what's needed (e.g., scatter plots with real data, photorealistic images).
π¨ The Source Format Philosophy
Why text-based diagrams win
| What matters | Mermaid in Markdown | Python / AI Image |
|---|---|---|
| Git diff readable | β | β binary blob |
| Editable without regenerating | β | β |
| Token efficient vs. prose | β smaller | β larger |
| Renders without a build step | β | β needs hosting |
| Parseable by AI without vision | β | β |
| Works in GitHub / GitLab / Notion | β | β οΈ if hosted |
| Accessible (screen readers) | β accTitle/accDescr | β οΈ needs alt text |
| Convertible to image later | β anytime | β already image |
The three-phase workflow
flowchart LR
accTitle: Three-Phase Documentation Workflow
accDescr: Phase 1 Mermaid in markdown is always required and is the source of truth. Phases 2 and 3 are optional downstream conversions for polished output.
p1["π Phase 1<br/>Mermaid in Markdown<br/>(ALWAYS β source of truth)"]
p2["π Phase 2<br/>Python Generated<br/>(optional β data charts)"]
p3["π¨ Phase 3<br/>AI Generated Visuals<br/>(optional β polish)"]
out["π Final Deliverable"]
p1 --> out
p1 -.->|"when needed"| p2
p1 -.->|"when needed"| p3
p2 --> out
p3 --> out
classDef required fill:#dbeafe,stroke:#2563eb,stroke-width:2px,color:#1e3a5f
classDef optional fill:#fef9c3,stroke:#ca8a04,stroke-width:2px,color:#713f12
classDef output fill:#dcfce7,stroke:#16a34a,stroke-width:2px,color:#14532d
class p1 required
class p2,p3 optional
class out output
Phase 1 is mandatory. Even if you proceed to Phase 2 or 3, the Mermaid source stays committed.
What Mermaid can express
Mermaid covers 24 diagram types. Almost every scientific relationship fits one:
| Use case | Diagram type | File |
|---|---|---|
| Experimental workflow / decision logic | Flowchart | references/diagrams/flowchart.md |
| Service interactions / API calls / messaging | Sequence | references/diagrams/sequence.md |
| Data model / schema | ER diagram | references/diagrams/er.md |
| State machine / lifecycle | State | references/diagrams/state.md |
| Project timeline / roadmap | Gantt | references/diagrams/gantt.md |
| Proportions / composition | Pie | references/diagrams/pie.md |
| System architecture (zoom levels) | C4 | references/diagrams/c4.md |
| Concept hierarchy / brainstorm | Mindmap | references/diagrams/mindmap.md |
| Chronological events / history | Timeline | references/diagrams/timeline.md |
| Class hierarchy / type relationships | Class | references/diagrams/class.md |
| User journey / satisfaction map | User Journey | references/diagrams/user_journey.md |
| Two-axis comparison / prioritization | Quadrant | references/diagrams/quadrant.md |
| Requirements traceability | Requirement | references/diagrams/requirement.md |
| Flow magnitude / resource distribution | Sankey | references/diagrams/sankey.md |
| Numeric trends / bar + line charts | XY Chart | references/diagrams/xy_chart.md |
| Component layout / spatial arrangement | Block | references/diagrams/block.md |
| Work item status / task columns | Kanban | references/diagrams/kanban.md |
| Cloud infrastructure / service topology | Architecture | references/diagrams/architecture.md |
| Multi-dimensional comparison / skills radar | Radar | references/diagrams/radar.md |
| Hierarchical proportions / budget | Treemap | references/diagrams/treemap.md |
| Binary protocol / data format | Packet | references/diagrams/packet.md |
| Git branching / merge strategy | Git Graph | references/diagrams/git_graph.md |
| Code-style sequence (programming syntax) | ZenUML | references/diagrams/zenuml.md |
| Multi-diagram composition patterns | Complex Examples | references/diagrams/complex_examples.md |
π‘ Pick the right type, not the easy one. Don't default to flowcharts for everything. A timeline beats a flowchart for chronological events. A sequence beats a flowchart for service interactions. Scan the table and match.
π§ Core workflow
Step 1: Identify the document type
Check if a template exists before writing from scratch:
| Document type | Template |
|---|---|
| Pull request record | templates/pull_request.md |
| Issue / bug / feature request | templates/issue.md |
| Sprint / project board | templates/kanban.md |
| Architecture decision (ADR) | templates/decision_record.md |
| Presentation / briefing | templates/presentation.md |
| Research paper / analysis | templates/research_paper.md |
| Project documentation | templates/project_documentation.md |
| How-to / tutorial | templates/how_to_guide.md |
| Status report | templates/status_report.md |
Step 2: Read the style guide
Before writing any .md file: read references/markdown_style_guide.md.
Key rules to internalize:
- One H1 per document β the title. Never more.
- Emoji on H2 headings only β one emoji per H2, none in H3/H4
- Cite everything β every external claim gets a footnote
[^N]with full URL - Bold sparingly β max 2-3 bold terms per paragraph, never full sentences
- Horizontal rule after every
</details>β mandatory - Tables over prose for comparisons, configurations, structured data
- Diagrams over walls of text β if it describes flow, structure, or relationships, add Mermaid
Step 3: Pick the diagram type and read its guide
Before creating any Mermaid diagram: read references/mermaid_style_guide.md.
Then open the specific type file (e.g., references/diagrams/flowchart.md) for the exemplar, tips, and copy-paste template.
Mandatory rules for every diagram:
accTitle: Short Name 3-8 Words
accDescr: One or two sentences explaining what this diagram shows.
- No
%%{init}directives β breaks GitHub dark mode - No inline
styleβ useclassDefonly - One emoji per node max β at the start of the label
snake_casenode IDs β match the label
Step 4: Write the document
Start from the template. Apply the markdown style guide. Place diagrams inline with related text β not in a separate "Figures" section.
Step 5: Commit as text
The .md file with embedded Mermaid is what gets committed. If you also generated a PNG or AI image, those are supplementary β the markdown is the source.
β οΈ Common pitfalls
Radar chart syntax (radar-beta)
WRONG:
radar
title Example
x-axis ["A", "B", "C"]
"Series" : [1, 2, 3]
CORRECT:
radar-beta
title Example
axis a["A"], b["B"], c["C"]
curve series["Series"]{1, 2, 3}
max 3
- Use
radar-betanotradar(the bare keyword doesn't exist) - Use
axisto define dimensions, notx-axis - Use
curveto define data series, not quoted labels with colon - No
accTitle/accDescrβ radar-beta doesn't support accessibility annotations; always add a descriptive italic paragraph above the diagram
XY Chart vs Radar confusion
| Diagram | Keyword | Axis syntax | Data syntax |
|---|---|---|---|
| XY Chart (bars/lines) | xychart-beta |
x-axis ["Label1", "Label2"] |
bar [10, 20] or line [10, 20] |
| Radar (spider/web) | radar-beta |
axis id["Label"] |
curve id["Label"]{10, 20} |
Forgetting accTitle/accDescr on supported types
Only some diagram types support accTitle/accDescr. For those that don't, always place a descriptive italic paragraph directly above the code block:
Radar chart comparing three methods across five performance dimensions. Note: Radar charts do not support accTitle/accDescr.
radar-beta
...
π Integration with other skills
With scientific-schematics
scientific-schematics generates AI-powered publication-quality images (PNG). Use the Mermaid diagram as the brief for the schematic:
Workflow:
1. Create the concept as Mermaid in .md (this skill β Phase 1)
2. Describe the same concept to scientific-schematics for a polished PNG (Phase 3)
3. Commit both β the .md as source, the PNG as a supplementary figure
With scientific-writing
When scientific-writing produces a manuscript, all diagrams and structural figures should use this skill's standards. The writing skill handles prose and citations; this skill handles visual structure.
Workflow:
1. Use scientific-writing to draft the manuscript
2. For every figure that shows a workflow, architecture, or relationship:
- Replace placeholder with a Mermaid diagram following this skill's guide
3. Use scientific-schematics only for figures that truly need photorealistic/complex rendering
With literature-review
Literature review produces summaries with lots of relationship data. Use this skill to:
- Create concept maps (Mindmap) of the literature landscape
- Show publication timelines (Timeline or Gantt)
- Compare methodologies (Quadrant or Radar)
- Diagram data flows described in papers (Sequence or Flowchart)
With any skill that produces output documents
Before finalizing any document from any skill, apply this skill's checklist:
- Does the document use a template? If so, did I start from the right one?
- Are all diagrams in Mermaid with
accTitle+accDescr? - No
%%{init}, no inlinestyle, onlyclassDef? - Are all external claims cited with
[^N]? - One H1, emoji on H2 only?
- Horizontal rules after every
</details>?
π Reference index
Style guides
| Guide | Path | Lines | What it covers |
|---|---|---|---|
| Markdown Style Guide | references/markdown_style_guide.md |
~733 | Headings, formatting, citations, tables, Mermaid integration, templates, quality checklist |
| Mermaid Style Guide | references/mermaid_style_guide.md |
~458 | Accessibility, emoji set, color classes, theme neutrality, type selection, complexity tiers |
Diagram type guides (24 types)
Each file contains: production-quality exemplar, tips specific to that type, and a copy-paste template.
references/diagrams/ β architecture, block, c4, class, complex_examples, er, flowchart, gantt, git_graph, kanban, mindmap, packet, pie, quadrant, radar, requirement, sankey, sequence, state, timeline, treemap, user_journey, xy_chart, zenuml
Document templates (9 types)
templates/ β decision_record, how_to_guide, issue, kanban, presentation, project_documentation, pull_request, research_paper, status_report
Examples
assets/examples/example-research-report.md β a complete scientific research report demonstrating proper heading hierarchy, multiple diagram types (flowchart, sequence, gantt), tables, footnote citations, collapsible sections, and all style guide rules applied.
π Attribution
All style guides, diagram type guides, and document templates in this skill are ported from the SuperiorByteWorks-LLC/agent-project repository under the Apache-2.0 License.
- Source: https://github.com/SuperiorByteWorks-LLC/agent-project
- Author: Clayton Young / Superior Byte Works, LLC (@borealBytes)
- License: Apache-2.0
This skill (as part of scientific-agent-skills) is distributed under the MIT License. The included Apache-2.0 content is compatible for downstream use with attribution retained, as preserved in the file headers throughout this skill.
[^1]: GitHub Blog. (2022). "Include diagrams in your Markdown files with Mermaid." https://github.blog/2022-02-14-include-diagrams-markdown-files-mermaid/
[^2]: Mermaid. "Mermaid Diagramming and Charting Tool." https://mermaid.js.org/
Other files in this skill
- assets/examples/example-research-report.md
- references/diagrams/architecture.md
- references/diagrams/block.md
- references/diagrams/c4.md
- references/diagrams/class.md
- references/diagrams/complex_examples.md
- references/diagrams/er.md
- references/diagrams/flowchart.md
- references/diagrams/gantt.md
- references/diagrams/git_graph.md
- references/diagrams/kanban.md
- references/diagrams/mindmap.md
- references/diagrams/packet.md
- references/diagrams/pie.md
- references/diagrams/quadrant.md
- references/diagrams/radar.md
- references/diagrams/requirement.md
- references/diagrams/sankey.md
- references/diagrams/sequence.md
- references/diagrams/state.md
- references/diagrams/timeline.md
- references/diagrams/treemap.md
- references/diagrams/user_journey.md
- references/diagrams/xy_chart.md
- references/diagrams/zenuml.md
- references/markdown_style_guide.md
- references/mermaid_style_guide.md
- templates/decision_record.md
- templates/how_to_guide.md
- templates/issue.md
- templates/kanban.md
- templates/presentation.md
- templates/project_documentation.md
- templates/pull_request.md
- templates/research_paper.md
- templates/status_report.md
assets/examples/example-research-report.md (verbatim)
CRISPR-Based Gene Editing Efficiency Analysis
Example research report β demonstrates markdown-mermaid-writing skill standards. All diagrams use Mermaid embedded in markdown as the source format.
π Overview
This report analyzes the efficiency of CRISPR-Cas9 gene editing across three cell line models under variable guide RNA (gRNA) conditions. Editing efficiency was quantified by T7E1 assay and next-generation sequencing (NGS) of on-target loci[^1].
Key findings:
- HEK293T cells show highest editing efficiency (mean 78%) across all gRNA designs
- GC content between 40β65% correlates with editing efficiency (r = 0.82)
- Off-target events occur at <0.1% frequency across all conditions tested
π Experimental workflow
CRISPR editing experiments followed a standardized five-stage protocol. Each stage has defined go/no-go criteria before proceeding.
flowchart TD
accTitle: CRISPR Editing Experimental Workflow
accDescr: Five-stage experimental pipeline from gRNA design through data analysis, with quality checkpoints between each stage.
design["𧬠Stage 1<br/>gRNA Design<br/>(CRISPRscan + Cas-OFFinder)"]
synth["βοΈ Stage 2<br/>Oligo Synthesis<br/>& Annealing"]
transfect["π¬ Stage 3<br/>Cell Transfection<br/>(Lipofectamine 3000)"]
screen["π§ͺ Stage 4<br/>Primary Screen<br/>(T7E1 assay)"]
ngs["π Stage 5<br/>NGS Validation<br/>(150 bp PE reads)"]
qc1{GC 40-65%?}
qc2{Yield β₯ 2 Β΅g?}
qc3{Viability β₯ 85%?}
qc4{Band visible?}
design --> qc1
qc1 -->|"β
Pass"| synth
qc1 -->|"β Redesign"| design
synth --> qc2
qc2 -->|"β
Pass"| transfect
qc2 -->|"β Re-synthesize"| synth
transfect --> qc3
qc3 -->|"β
Pass"| screen
qc3 -->|"β Optimize"| transfect
screen --> qc4
qc4 -->|"β
Pass"| ngs
qc4 -->|"β Repeat"| screen
classDef stage fill:#dbeafe,stroke:#2563eb,stroke-width:2px,color:#1e3a5f
classDef gate fill:#fef9c3,stroke:#ca8a04,stroke-width:2px,color:#713f12
classDef fail fill:#fee2e2,stroke:#dc2626,stroke-width:2px,color:#7f1d1d
class design,synth,transfect,screen,ngs stage
class qc1,qc2,qc3,qc4 gate
π¬ Methods
Cell lines and culture
Three cell lines were used: HEK293T (human embryonic kidney), K562 (chronic myelogenous leukemia), and Jurkat (T-lymphocyte). All lines were maintained in RPMI-1640 with 10% FBS at 37Β°C / 5% COβ[^2].
gRNA design and efficiency prediction
gRNAs targeting the EMX1 locus were designed using CRISPRscan[^3] with the following criteria:
| Criterion | Threshold | Rationale |
|---|---|---|
| GC content | 40β65% | Optimal Tm and Cas9 binding |
| CRISPRscan score | β₯ 0.6 | Predicted on-target activity |
| Off-target sites | β€ 5 (β€3 mismatches) | Reduce off-target editing risk |
| Homopolymer runs | None (>4 nt) | Prevents premature transcription stop |
Transfection protocol
RNP complexes were assembled at 1:1.2 molar ratio (Cas9:gRNA) and delivered by lipofection. Cells were harvested 72 hours post-transfection for genomic DNA extraction.
Analysis pipeline
sequenceDiagram
accTitle: NGS Data Analysis Pipeline
accDescr: Sequence of computational steps from raw FASTQ files through variant calling to final efficiency report.
participant raw as π₯ Raw FASTQ
participant qc as π FastQC
participant trim as βοΈ Trimmomatic
participant align as πΊοΈ BWA-MEM2
participant call as βοΈ CRISPResso2
participant report as π Report
raw->>qc: Per-base quality scores
qc-->>trim: Flag low-Q reads (Q<20)
trim->>align: Cleaned reads
align->>align: Index reference genome (hg38)
align->>call: BAM + target region BED
call->>call: Quantify indel frequency
call-->>report: Editing efficiency (%)
call-->>report: Off-target events
report-->>report: Statistical summary
π Results
Editing efficiency by cell line
| Cell line | n (replicates) | Mean efficiency (%) | SD (%) | Range (%) |
|---|---|---|---|---|
| HEK293T | 6 | 78.4 | 4.2 | 71.2β84.6 |
| K562 | 6 | 52.1 | 8.7 | 38.4β63.2 |
| Jurkat | 6 | 31.8 | 11.3 | 14.2β47.5 |
HEK293T cells showed significantly higher editing efficiency than both K562 (p < 0.001) and Jurkat (p < 0.001) lines by one-way ANOVA with Tukey post-hoc correction.
Effect of GC content on efficiency
GC content between 40β65% was strongly correlated with editing efficiency (Pearson r = 0.82, p < 0.0001, n = 48 gRNAs).
xychart-beta
accTitle: Editing Efficiency vs gRNA GC Content
accDescr: Bar chart showing mean editing efficiency grouped by GC content bins, demonstrating optimal performance in the 40 to 65 percent GC range
title "Mean Editing Efficiency by GC Content Bin (HEK293T)"
x-axis ["< 30%", "30β40%", "40β50%", "50β65%", "> 65%"]
y-axis "Editing Efficiency (%)" 0 --> 100
bar [18, 42, 76, 81, 38]
Timeline of key experimental milestones
timeline
accTitle: Experiment Timeline β CRISPR Efficiency Study
accDescr: Chronological milestones from study design through manuscript submission across six months
section Month 1
Study design and gRNA library design : 48 gRNAs across 3 target loci
Cell line authentication : STR profiling confirmed all three lines
section Month 2
gRNA synthesis and QC : 46/48 gRNAs passed yield threshold
Pilot transfections (HEK293T) : Optimized lipofection conditions
section Month 3
Full transfection series : All 3 cell lines, all 46 gRNAs, 6 replicates
T7E1 primary screening : Passed go/no-go for all conditions
section Month 4
NGS library preparation : 276 samples processed
Sequencing run (NovaSeq) : 150 bp PE, mean 50k reads/sample
section Month 5
Bioinformatic analysis : CRISPResso2 pipeline
Statistical analysis : ANOVA, correlation, regression
section Month 6
Manuscript preparation : This report
π Discussion
Why HEK293T outperforms suspension lines
HEK293T's superior editing efficiency relative to K562 and Jurkat likely reflects three factors[^4]:
- Adherent morphology β enables more uniform lipofection contact
- High transfection permissiveness β HEK293T expresses the SV40 large T antigen, which may facilitate nuclear import
- Cell cycle distribution β higher proportion in S/G2 phase where HDR is favored
Off-target editing was assessed by GUIDE-seq at the 5 highest-activity gRNAs. No off-target sites exceeding 0.1% editing frequency were detected. The three potential sites flagged by Cas-OFFinder (β€2 mismatches) showed 0.00%, 0.02%, and 0.04% indel frequencies β all below the assay noise floor of 0.05%.
Full GUIDE-seq data available in supplementary data package (GEO accession pending).
</details>Comparison with published benchmarks
Radar chart comparing three CRISPR delivery methods across five performance dimensions. Note: Radar charts do not support accTitle/accDescr β description provided above.
radar-beta
title Performance vs. Published Methods
axis eff["Efficiency"], spec["Specificity"], del["Delivery ease"], cost["Cost"], viab["Cell viability"]
curve this_study["This study (RNP + Lipo)"]{78, 95, 80, 85, 90}
curve plasmid["Plasmid Cas9 (lit.)"]{55, 70, 90, 95, 75}
curve electroporation["Electroporation RNP (lit.)"]{88, 96, 50, 60, 65}
max 100
graticule polygon
ticks 5
showLegend true
π― Conclusions
- RNP-lipofection in HEK293T achieves >75% CRISPR editing efficiency β competitive with electroporation without the associated viability cost
- gRNA GC content is the single strongest predictor of editing efficiency in our dataset (r = 0.82)
- This protocol is not directly transferable to suspension lines without further optimization; K562 and Jurkat require electroporation or viral delivery for comparable efficiency
π References
[^1]: Ran, F.A. et al. (2013). "Genome engineering using the CRISPR-Cas9 system." Nature Protocols, 8(11), 2281β2308. https://doi.org/10.1038/nprot.2013.143
[^2]: ATCC. (2024). "Cell Line Authentication and Quality Control." https://www.atcc.org/resources/technical-documents/cell-line-authentication
[^3]: Moreno-Mateos, M.A. et al. (2015). "CRISPRscan: designing highly efficient sgRNAs for CRISPR-Cas9 targeting in vivo." Nature Methods, 12(10), 982β988. https://doi.org/10.1038/nmeth.3543
[^4]: Molla, K.A. & Yang, Y. (2019). "CRISPR/Cas-Mediated Base Editing: Technical Considerations and Practical Applications." Trends in Biotechnology, 37(10), 1121β1142. https://doi.org/10.1016/j.tibtech.2019.03.008
references/diagrams/architecture.md (verbatim)
<!-- Source: https://github.com/SuperiorByteWorks-LLC/agent-project | License: Apache-2.0 | Author: Clayton Young / Superior Byte Works, LLC (Boreal Bytes) -->Architecture Diagram
Back to Style Guide β Read the style guide first for emoji, color, and accessibility rules.
Syntax keyword: architecture-beta
Best for: Cloud infrastructure, service topology, deployment architecture, network layout
When NOT to use: Logical system boundaries (use C4), component layout without cloud semantics (use Block)
β οΈ Accessibility: Architecture diagrams do not support
accTitle/accDescr. Always place a descriptive italic Markdown paragraph directly above the code block.
Exemplar Diagram
Architecture diagram showing a cloud-hosted web application with a load balancer, API server, database, and cache deployed within a VPC:
architecture-beta
group cloud(cloud)[AWS Cloud]
group vpc(cloud)[VPC] in cloud
service lb(internet)[Load Balancer] in vpc
service api(server)[API Server] in vpc
service db(database)[PostgreSQL] in vpc
service cache(disk)[Redis Cache] in vpc
lb:R --> L:api
api:R --> L:db
api:B --> T:cache
Tips
- Use
groupfor logical boundaries (VPC, region, cluster, availability zone) - Use
servicefor individual components - Direction annotations on connections:
:L(left),:R(right),:T(top),:B(bottom) - Built-in icon types:
cloud,server,database,internet,disk - Nest groups with
in parent_group - Labels must be plain text β no emoji and no hyphens in
[]labels (parser treats-as an edge operator) - Use
-->for directional arrows,--for undirected edges - Keep to 6β8 services per diagram
- Always pair with a Markdown text description above for screen readers
Template
Description of the infrastructure topology and key components:
architecture-beta
group region(cloud)[Cloud Region]
service frontend(internet)[Web Frontend] in region
service backend(server)[API Server] in region
service datastore(database)[Database] in region
frontend:R --> L:backend
backend:R --> L:datastore
Complex Example
Multi-region cloud deployment with 3 nested groups (2 regional clusters + shared services) showing 9 services, cross-region database replication, CDN distribution, and centralized monitoring. Demonstrates how nested group + in syntax creates clear infrastructure boundaries:
architecture-beta
group cloud(cloud)[AWS Platform]
group east(cloud)[US East Region] in cloud
service lb_east(internet)[Load Balancer East] in east
service app_east(server)[App Server East] in east
service db_primary(database)[Primary Database] in east
group west(cloud)[US West Region] in cloud
service lb_west(internet)[Load Balancer West] in west
service app_west(server)[App Server West] in west
service db_replica(database)[Replica Database] in west
group shared(cloud)[Shared Services] in cloud
service cdn(internet)[CDN Edge] in shared
service monitor(server)[Monitoring] in shared
service queue(server)[Message Queue] in shared
cdn:B --> T:lb_east
cdn:B --> T:lb_west
lb_east:R --> L:app_east
lb_west:R --> L:app_west
app_east:B --> T:db_primary
app_west:B --> T:db_replica
db_primary:R --> L:db_replica
app_east:R --> L:queue
app_west:R --> L:queue
monitor:B --> T:app_east
Why this works
- Nested groups mirror real infrastructure β cloud > region > services is exactly how teams think about multi-region deployments. The nesting creates clear blast radius boundaries.
- Plain text labels only β architecture diagrams parse-fail with emoji in
[]labels. All visual distinction comes from the group nesting and icon types (internet,server,database). - Directional annotations prevent overlap β
:B --> T:(bottom-to-top),:R --> L:(right-to-left) control where edges connect. Without these, Mermaid stacks edges on top of each other. - Cross-region replication is explicit β the
db_primary:R --> L:db_replicaedge is the most important infrastructure detail and reads clearly as a horizontal connection between regions.
references/diagrams/block.md (verbatim)
<!-- Source: https://github.com/SuperiorByteWorks-LLC/agent-project | License: Apache-2.0 | Author: Clayton Young / Superior Byte Works, LLC (Boreal Bytes) -->Block Diagram
Back to Style Guide β Read the style guide first for emoji, color, and accessibility rules.
Syntax keyword: block-beta
Best for: System block composition, layered architectures, component topology where spatial layout matters
When NOT to use: Process flows (use Flowchart), infrastructure with cloud icons (use Architecture)
β οΈ Accessibility: Block diagrams do not support
accTitle/accDescr. Always place a descriptive italic Markdown paragraph directly above the code block.
Exemplar Diagram
Block diagram showing a three-tier web application architecture from client-facing interfaces through application services to data storage, with emoji labels indicating component types:
block-beta
columns 3
block:client:3
columns 3
browser["π Browser"]
mobile["π± Mobile App"]
cli["β¨οΈ CLI Tool"]
end
space:3
block:app:3
columns 3
api["π₯οΈ API Server"]
worker["βοΈ Worker"]
cache["β‘ Redis Cache"]
end
space:3
block:data:3
columns 2
db[("πΎ PostgreSQL")]
storage["π¦ Object Storage"]
end
browser --> api
mobile --> api
cli --> api
api --> worker
api --> cache
worker --> db
api --> db
worker --> storage
Tips
- Use
columns Nto control the layout grid - Use
space:Nfor empty cells (alignment/spacing) - Nest
block:name:span { ... }for grouped sections - Connect blocks with
-->arrows - Use emoji in labels
["π§ Component"]for visual distinction - Use cylinder
("text")syntax for databases within blocks - Keep to 3β4 rows with 3β4 columns for readability
- Always pair with a Markdown text description above for screen readers
Template
Description of the system layers and how components connect:
block-beta
columns 3
block:layer1:3
columns 3
comp_a["π Component A"]
comp_b["βοΈ Component B"]
comp_c["π¦ Component C"]
end
space:3
block:layer2:3
columns 2
comp_d["πΎ Component D"]
comp_e["π§ Component E"]
end
comp_a --> comp_d
comp_b --> comp_d
comp_c --> comp_e
Complex Example
Enterprise platform architecture rendered as a 5-tier block diagram with 15 components. Each tier is a block group spanning the full width, with internal columns controlling component layout. Connections show the primary data flow paths between tiers:
block-beta
columns 4
block:clients:4
columns 4
browser["π Browser"]
mobile["π± Mobile App"]
partner["π Partner API"]
admin["π Admin Console"]
end
space:4
block:gateway:4
columns 2
apigw["π API **Gateway**"]
auth["π Auth Service"]
end
space:4
block:services:4
columns 4
user_svc["π€ User Service"]
order_svc["π Order Service"]
product_svc["π¦ Product Service"]
notify_svc["π€ Notification Service"]
end
space:4
block:data:4
columns 3
postgres[("πΎ PostgreSQL")]
redis["β‘ Redis Cache"]
elastic["π Elasticsearch"]
end
space:4
block:infra:4
columns 3
mq["π₯ Message Queue"]
logs["π Log Aggregator"]
metrics["π Metrics Store"]
end
browser --> apigw
mobile --> apigw
partner --> apigw
admin --> auth
apigw --> auth
apigw --> user_svc
apigw --> order_svc
apigw --> product_svc
order_svc --> notify_svc
user_svc --> postgres
order_svc --> postgres
product_svc --> elastic
order_svc --> redis
notify_svc --> mq
order_svc --> mq
mq --> logs
Why this works
- 5 tiers read top-to-bottom like a network diagram β clients, gateway, services, data, infrastructure. Each tier is a block spanning the full width with its own column layout.
space:4creates visual separation between tiers without unnecessary lines or borders, keeping the diagram clean and scannable.- Cylinder syntax
("text")for databases β PostgreSQL renders as a cylinder, instantly recognizable as a data store. Other components use standard rectangles. - Connections show real data paths β not every possible connection, just the primary flows. A fully-connected diagram would be unreadable; this shows the key paths an engineer would trace during debugging.
references/diagrams/c4.md (verbatim)
<!-- Source: https://github.com/SuperiorByteWorks-LLC/agent-project | License: Apache-2.0 | Author: Clayton Young / Superior Byte Works, LLC (Boreal Bytes) -->C4 Diagram
Back to Style Guide β Read the style guide first for emoji, color, and accessibility rules.
Syntax keyword: C4Context, C4Container, C4Component
Best for: System architecture at varying zoom levels β context, containers, components
When NOT to use: Infrastructure topology (use Architecture), runtime sequences (use Sequence)
Exemplar Diagram β System Context
C4Context
accTitle: Online Store System Context
accDescr: C4 context diagram showing how a customer interacts with the store and its external payment dependency
title Online Store - System Context
Person(customer, "Customer", "Places orders")
System(store, "Online Store", "Catalog and checkout")
System_Ext(payment, "Payment Provider", "Card processing")
Rel(customer, store, "Orders", "HTTPS")
Rel(store, payment, "Pays", "API")
UpdateRelStyle(customer, store, $offsetY="-40", $offsetX="-30")
UpdateRelStyle(store, payment, $offsetY="-40", $offsetX="-30")
C4 Zoom Levels
| Level | Keyword | Shows | Audience |
|---|---|---|---|
| Context | C4Context |
Systems + external actors | Everyone |
| Container | C4Container |
Apps, databases, queues within a system | Technical leads |
| Component | C4Component |
Internal modules within a container | Developers |
Tips
- Use
Person()for human actors - Use
System()for internal systems,System_Ext()for external - Use
Container(),ContainerDb(),ContainerQueue()at the container level - Label relationships with verbs and protocols:
"Reads from", "SQL/TLS" - Use
Container_Boundary(id, "name") { ... }to group containers - Keep descriptions short β long text causes label overlaps
- Limit to 4β5 elements at the Context level to avoid crowding
- Avoid emoji in C4 labels β the C4 renderer handles its own styling
- Use
UpdateRelStyle()to adjust label positions if overlaps occur
Template
C4Context
accTitle: Your System Context
accDescr: Describe the system boundaries and external interactions
Person(user, "User", "Role description")
System(main_system, "Your System", "What it does")
System_Ext(external, "External Service", "What it provides")
Rel(user, main_system, "Uses", "HTTPS")
Rel(main_system, external, "Calls", "API")
Complex Example
A C4 Container diagram for an e-commerce platform with 3 Container_Boundary groups, 10 containers, and 2 external systems. Shows how to use boundaries to organize services by layer, with UpdateRelStyle offsets preventing label overlaps.
C4Container
accTitle: E-Commerce Platform Container View
accDescr: C4 container diagram showing web and mobile frontends, core backend services, and data stores with external payment and email dependencies
Person(customer, "Customer", "Shops online")
Container_Boundary(frontend, "Frontend") {
Container(spa, "Web App", "React", "Single-page app")
Container(bff, "BFF API", "Node.js", "Backend for frontend")
}
Container_Boundary(services, "Core Services") {
Container(order_svc, "Order Service", "Go", "Order processing")
Container(catalog_svc, "Product Catalog", "Go", "Product data")
Container(user_svc, "User Service", "Go", "Auth and profiles")
}
Container_Boundary(data, "Data Layer") {
ContainerDb(pg, "PostgreSQL", "SQL", "Primary data store")
ContainerDb(redis, "Redis", "Cache", "Session and cache")
ContainerDb(search, "Elasticsearch", "Search", "Product search")
}
System_Ext(payment_gw, "Payment Gateway", "Card processing")
System_Ext(email_svc, "Email Service", "Transactional email")
Rel(customer, spa, "Browses", "HTTPS")
Rel(spa, bff, "Calls", "GraphQL")
Rel(bff, order_svc, "Places orders", "gRPC")
Rel(bff, catalog_svc, "Queries", "gRPC")
Rel(bff, user_svc, "Authenticates", "gRPC")
Rel(order_svc, pg, "Reads/writes", "SQL")
Rel(order_svc, payment_gw, "Charges", "API")
Rel(order_svc, email_svc, "Sends", "SMTP")
Rel(catalog_svc, search, "Indexes", "REST")
Rel(user_svc, redis, "Sessions", "TCP")
Rel(catalog_svc, pg, "Reads", "SQL")
UpdateRelStyle(customer, spa, $offsetY="-40", $offsetX="-50")
UpdateRelStyle(spa, bff, $offsetY="-30", $offsetX="10")
UpdateRelStyle(bff, order_svc, $offsetY="-30", $offsetX="-40")
UpdateRelStyle(bff, catalog_svc, $offsetY="-30", $offsetX="10")
UpdateRelStyle(bff, user_svc, $offsetY="-30", $offsetX="50")
UpdateRelStyle(order_svc, pg, $offsetY="-30", $offsetX="-50")
UpdateRelStyle(order_svc, payment_gw, $offsetY="-30", $offsetX="10")
UpdateRelStyle(order_svc, email_svc, $offsetY="10", $offsetX="10")
UpdateRelStyle(catalog_svc, search, $offsetY="-30", $offsetX="10")
UpdateRelStyle(user_svc, redis, $offsetY="-30", $offsetX="10")
UpdateRelStyle(catalog_svc, pg, $offsetY="10", $offsetX="30")
Why this works
- Container_Boundary groups map to deployment units β frontend, core services, and data layer each correspond to real infrastructure boundaries (CDN, Kubernetes namespace, managed databases)
- Every
RelhasUpdateRelStyleβ C4's auto-layout stacks labels on top of each other by default. Offset every relationship to prevent overlaps, even if it seems fine at first (adding elements later will shift things) - Descriptions are kept to 1-3 words β "Card processing", "Session and cache", "Auth and profiles". Long descriptions are the #1 cause of C4 rendering issues
- Container types are semantic β
ContainerDbfor databases gives them the cylinder icon,Containerfor services. The C4 renderer provides its own visual differentiation
references/diagrams/class.md (verbatim)
<!-- Source: https://github.com/SuperiorByteWorks-LLC/agent-project | License: Apache-2.0 | Author: Clayton Young / Superior Byte Works, LLC (Boreal Bytes) -->Class Diagram
Back to Style Guide β Read the style guide first for emoji, color, and accessibility rules.
Syntax keyword: classDiagram
Best for: Object-oriented design, type hierarchies, interface contracts, domain models
When NOT to use: Database schemas (use ER), runtime behavior (use Sequence)
Exemplar Diagram
classDiagram
accTitle: Payment Processing Class Hierarchy
accDescr: Interface and abstract base class with two concrete implementations for credit card and digital wallet payment processing
class PaymentProcessor {
<<interface>>
+processPayment(amount) bool
+refund(transactionId) bool
+getStatus(transactionId) string
}
class BaseProcessor {
<<abstract>>
#apiKey: string
#timeout: int
+validateAmount(amount) bool
#logTransaction(tx) void
}
class CreditCardProcessor {
-gateway: string
+processPayment(amount) bool
+refund(transactionId) bool
-tokenizeCard(card) string
}
class DigitalWalletProcessor {
-provider: string
+processPayment(amount) bool
+refund(transactionId) bool
-initiateHandshake() void
}
PaymentProcessor <|.. BaseProcessor : implements
BaseProcessor <|-- CreditCardProcessor : extends
BaseProcessor <|-- DigitalWalletProcessor : extends
style PaymentProcessor fill:#ede9fe,stroke:#7c3aed,stroke-width:2px,color:#3b0764
style BaseProcessor fill:#dbeafe,stroke:#2563eb,stroke-width:2px,color:#1e3a5f
style CreditCardProcessor fill:#dcfce7,stroke:#16a34a,stroke-width:2px,color:#14532d
style DigitalWalletProcessor fill:#dcfce7,stroke:#16a34a,stroke-width:2px,color:#14532d
Tips
- Use
<<interface>>and<<abstract>>stereotypes for clarity - Show visibility:
+public,-private,#protected - Keep to 4β6 classes per diagram β split larger hierarchies
- Use
style ClassName fill:...,stroke:...,color:...for light semantic coloring:- π£ Purple for interfaces/abstractions
- π΅ Blue for base/abstract classes
- π’ Green for concrete implementations
- Relationship arrows:
<|--inheritance (extends)<|..implementation (implements)*--composition Β·o--aggregation Β·-->dependency
Template
classDiagram
accTitle: Your Title Here
accDescr: Describe the class hierarchy and the key relationships between types
class InterfaceName {
<<interface>>
+methodOne() ReturnType
+methodTwo(param) ReturnType
}
class ConcreteClass {
-privateField: Type
+methodOne() ReturnType
+methodTwo(param) ReturnType
}
InterfaceName <|.. ConcreteClass : implements
Complex Example
An event-driven notification platform with 11 classes organized into 3 namespace groups β core orchestration, delivery channels, and data models. Shows interface implementation, composition, and dependency relationships across layers.
classDiagram
accTitle: Event-Driven Notification Platform
accDescr: Multi-namespace class hierarchy for a notification system showing core orchestration, four delivery channel implementations, and supporting data models with composition and dependency relationships
namespace Core {
class NotificationService {
-queue: NotificationQueue
-registry: ChannelRegistry
+dispatch(notification) bool
+scheduleDelivery(notification, time) void
+getDeliveryStatus(id) DeliveryStatus
}
class NotificationQueue {
-pending: List~Notification~
-maxRetries: int
+enqueue(notification) void
+dequeue() Notification
+retry(attempt) bool
}
class ChannelRegistry {
-channels: Map~string, Channel~
+register(name, channel) void
+resolve(type) Channel
+healthCheck() Map~string, bool~
}
}
namespace Channels {
class Channel {
<<interface>>
+send(notification, recipient) DeliveryAttempt
+getStatus(attemptId) DeliveryStatus
+validateRecipient(recipient) bool
}
class EmailChannel {
-smtpHost: string
-templateEngine: TemplateEngine
+send(notification, recipient) DeliveryAttempt
+getStatus(attemptId) DeliveryStatus
+validateRecipient(recipient) bool
}
class SMSChannel {
-provider: string
-rateLimit: int
+send(notification, recipient) DeliveryAttempt
+getStatus(attemptId) DeliveryStatus
+validateRecipient(recipient) bool
}
class PushChannel {
-firebaseKey: string
-apnsKey: string
+send(notification, recipient) DeliveryAttempt
+getStatus(attemptId) DeliveryStatus
+validateRecipient(recipient) bool
}
class WebhookChannel {
-signingSecret: string
-timeout: int
+send(notification, recipient) DeliveryAttempt
+getStatus(attemptId) DeliveryStatus
+validateRecipient(recipient) bool
}
}
namespace Models {
class Notification {
+id: uuid
+channel: string
+subject: string
+body: string
+priority: string
+createdAt: timestamp
}
class Recipient {
+id: uuid
+email: string
+phone: string
+deviceTokens: List~string~
+preferences: Map~string, bool~
}
class DeliveryAttempt {
+id: uuid
+notificationId: uuid
+recipientId: uuid
+status: DeliveryStatus
+attemptNumber: int
+sentAt: timestamp
}
class DeliveryStatus {
<<enumeration>>
QUEUED
SENDING
DELIVERED
FAILED
BOUNCED
}
}
NotificationService *-- NotificationQueue : contains
NotificationService *-- ChannelRegistry : contains
ChannelRegistry --> Channel : resolves
Channel <|.. EmailChannel : implements
Channel <|.. SMSChannel : implements
Channel <|.. PushChannel : implements
Channel <|.. WebhookChannel : implements
Channel ..> Notification : receives
Channel ..> Recipient : delivers to
Channel ..> DeliveryAttempt : produces
DeliveryAttempt --> DeliveryStatus : has
style Channel fill:#ede9fe,stroke:#7c3aed,stroke-width:2px,color:#3b0764
style DeliveryStatus fill:#ede9fe,stroke:#7c3aed,stroke-width:2px,color:#3b0764
style NotificationService fill:#dbeafe,stroke:#2563eb,stroke-width:2px,color:#1e3a5f
style NotificationQueue fill:#dbeafe,stroke:#2563eb,stroke-width:2px,color:#1e3a5f
style ChannelRegistry fill:#dbeafe,stroke:#2563eb,stroke-width:2px,color:#1e3a5f
style EmailChannel fill:#dcfce7,stroke:#16a34a,stroke-width:2px,color:#14532d
style SMSChannel fill:#dcfce7,stroke:#16a34a,stroke-width:2px,color:#14532d
style PushChannel fill:#dcfce7,stroke:#16a34a,stroke-width:2px,color:#14532d
style WebhookChannel fill:#dcfce7,stroke:#16a34a,stroke-width:2px,color:#14532d
style Notification fill:#f3f4f6,stroke:#6b7280,stroke-width:2px,color:#1f2937
style Recipient fill:#f3f4f6,stroke:#6b7280,stroke-width:2px,color:#1f2937
style DeliveryAttempt fill:#f3f4f6,stroke:#6b7280,stroke-width:2px,color:#1f2937
Why this works
- 3 namespaces mirror architectural layers β Core (orchestration), Channels (delivery implementations), Models (data). A developer can scan one namespace without reading the others.
- Color encodes the role β purple for interfaces/enums, blue for core services, green for concrete implementations, gray for data models. The pattern is instantly recognizable.
- Relationship types are deliberate β composition (
*--) for "owns and manages", implementation (<|..) for "fulfills contract", dependency (..>) for "uses at runtime". Each arrow type carries meaning.
references/diagrams/git_graph.md (verbatim)
<!-- Source: https://github.com/SuperiorByteWorks-LLC/agent-project | License: Apache-2.0 | Author: Clayton Young / Superior Byte Works, LLC (Boreal Bytes) -->Git Graph
Back to Style Guide β Read the style guide first for emoji, color, and accessibility rules.
Syntax keyword: gitGraph
Best for: Branching strategies, merge workflows, release processes, git-flow visualization
When NOT to use: General processes (use Flowchart), project timelines (use Gantt)
Exemplar Diagram
gitGraph
accTitle: Trunk-Based Development Workflow
accDescr: Git history showing short-lived feature branches merging into main with release tags demonstrating trunk-based development
commit id: "init"
commit id: "setup CI"
branch feature/auth
checkout feature/auth
commit id: "add login"
commit id: "add tests"
checkout main
merge feature/auth id: "merge auth" tag: "v1.0"
commit id: "update deps"
branch feature/dashboard
checkout feature/dashboard
commit id: "add charts"
commit id: "add filters"
checkout main
merge feature/dashboard id: "merge dash"
commit id: "perf fixes" tag: "v1.1"
Tips
- Use descriptive
id:labels on commits - Add
tag:for release versions - Branch names should match your actual convention (
feature/,fix/,release/) - Show the ideal workflow β this is prescriptive, not descriptive
- Use
type: HIGHLIGHTon important merge commits - Keep to 10β15 commits maximum for readability
Template
gitGraph
accTitle: Your Title Here
accDescr: Describe the branching strategy and merge pattern
commit id: "initial"
commit id: "second commit"
branch feature/your-feature
checkout feature/your-feature
commit id: "feature work"
commit id: "add tests"
checkout main
merge feature/your-feature id: "merge feature" tag: "v1.0"
references/diagrams/mindmap.md (verbatim)
<!-- Source: https://github.com/SuperiorByteWorks-LLC/agent-project | License: Apache-2.0 | Author: Clayton Young / Superior Byte Works, LLC (Boreal Bytes) -->Mindmap
Back to Style Guide β Read the style guide first for emoji, color, and accessibility rules.
Syntax keyword: mindmap
Best for: Brainstorming, concept organization, knowledge hierarchies, topic breakdown
When NOT to use: Sequential processes (use Flowchart), timelines (use Timeline)
β οΈ Accessibility: Mindmaps do not support
accTitle/accDescr. Always place a descriptive italic Markdown paragraph directly above the code block.
Exemplar Diagram
Mindmap showing a platform engineering team's key responsibility areas organized into infrastructure, developer experience, security, and observability domains:
mindmap
root((ποΈ Platform Engineering))
βοΈ Infrastructure
Kubernetes clusters
Service mesh
Load balancing
Auto-scaling
π§ Developer Experience
CI/CD pipelines
Local dev environments
Internal CLI tools
Documentation
π Security
Secret management
Network policies
Vulnerability scanning
Access control
π Observability
Metrics collection
Log aggregation
Distributed tracing
Alerting rules
Tips
- Keep to 3β4 main branches with 3β5 sub-items each
- Use emoji on branch headers for visual distinction
- Don't nest deeper than 3 levels
- Root node uses
(( ))for circle shape - Always pair with a Markdown text description above for screen readers
Template
Description of what this mindmap shows and the key categories it covers:
mindmap
root((π― Central Concept))
π Branch One
Sub-item A
Sub-item B
Sub-item C
π§ Branch Two
Sub-item D
Sub-item E
π Branch Three
Sub-item F
Sub-item G
Sub-item H
Back to K-Dense-AI/scientific-agent-skills (AI Scientist skills) or Agent skills.